Effie Apostolou, PhD
Assistant Professor of Molecular Biology in Medicine
Department of Medicine
Division of Hematology/Oncology
Cancer Center
Weill Cornell Medical College
Research
RESEARCH FOCUS
Somatic cell reprogramming is the process by which enforced expression of defined embryonic transcription factors (TF) in somatic cells changes their fate to induced pluripotent stem cells (iPSC).
APPROACH
We use high-throughput sequencing techniques such as 4C-Seq, HiC, ChIP-seq and RNA-seq. We also employ biochemical, molecular, and cell biology assays, as well as novel mouse genetics tools.
PROJECTS
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Regulation of imprinted gene expression.
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Coregulation of linage-related genes during differentiation.
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Role of pluripotency factors and cofactors in establishment and maintenance of interactions
People
Effie Apostolou, PhD
Principal Investigator
Dafne Campigli di
Giammartino, PhD
NYSCF Postdoctoral Fellow
Boaz Aronson, MD/PhD
Postdoctoral Researcher
Alex Polyzos, PhD
Computational Postdoctoral Researcher
Laurianne Scourzic, PhD
Postdoctoral Researcher
Dylan Murphy
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PhD Student
Veevek Shah​
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Lab Manager
Bobbie Pelham-Webb
MD/PhD Student
News
09/23/2019
Our paper on 3D-enhancer rewiring during reprogramming is out in Nature Cell Biology. Great work everyone!
Link for the article: here
Link for commentary: here
03/05/19
Bobbie is awarded an NIH F30 Fellowship from the National Institute for Child Health & Human Development (NICHD) for her work on Mitotic Bookmarking. Congrats Bobbie!
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03/01/18
Our paper on Mitotic Bookmarking is among the 10 Best of Cell Reports in 2017!
Download the PDF to see all 10 articles: here
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06/22/17
Laurianne is awarded the Lady Tata Memorial Trust Fellowship. Congratulations Laurianne!
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10/04/16
Effie gets the NIH Director's New Innovator award!!! Big news for the lab & big celebrations :)
See the full list of Awardees: here
See featuring article: here
Contact
Effie Apostolou
Weill Cornell Medical College
Belfer Research Building, Room 1418
413 East 69th Street,New York, NY 10021
| Tel: 646-962-6235